Eleanor M Dunican Selected Research

Asthma (Bronchial Asthma)

5/2024	A common polymorphism in the Intelectin-1 gene influences mucus plugging in severe asthma.
4/2024	Utility of eosinophil peroxidase as a biomarker of eosinophilic inflammation in asthma.
12/2023	A Novel Air Trapping Segment Score Identifies Opposing Effects of Obesity and Eosinophilia on Air Trapping in Asthma.
1/2022	Mucus Plugs in Asthma at CT Associated with Regional Ventilation Defects at 3He MRI.
1/2019	Refractory airway type 2 inflammation in a large subgroup of asthmatic patients treated with inhaled corticosteroids.
1/2019	Extracellular DNA, Neutrophil Extracellular Traps, and Inflammasome Activation in Severe Asthma.
11/2018	Autopsy and Imaging Studies of Mucus in Asthma. Lessons Learned about Disease Mechanisms and the Role of Mucus in Airflow Obstruction.
1/2018	Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction.
1/2017	Asthma and corticosteroids: time for a more precise approach to treatment.
11/2016	Abnormalities in MUC5AC and MUC5B Protein in Airway Mucus in Asthma.

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Eleanor M Dunican Research Topics

Disease

11	Asthma (Bronchial Asthma) 05/2024 - 10/2016
6	Inflammation (Inflammations) 04/2024 - 02/2015
1	Body Weight (Weight, Body) 01/2019
1	Eosinophilia 01/2018
1	Chronic Obstructive Pulmonary Disease (COPD) 01/2018

Drug/Important Bio-Agent (IBA)

5	Biomarkers (Surrogate Marker)IBA 05/2024 - 10/2016
3	Proteins (Proteins, Gene)FDA Link 05/2024 - 11/2016
3	CytokinesIBA 01/2019 - 10/2016
3	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2019 - 01/2017
2	DNA (Deoxyribonucleic Acid)IBA 01/2019 - 02/2015
1	mepolizumabIBA 04/2024
1	Eosinophil PeroxidaseIBA 04/2024
1	Dihydrotachysterol (AT 10)IBA 12/2023
1	HeliumIBA 01/2022
1	InflammasomesIBA 01/2019
1	Immunoglobulin E (IgE)IBA 01/2019
1	SteroidsIBA 01/2019
1	Caspase 1 (ICE Protease)IBA 01/2019
1	Expectorants (Mucolytics)IBA 11/2018
1	Serum Amyloid A Protein (Serum Amyloid A)IBA 01/2018
1	Oxidants (Oxidizing Agents)IBA 01/2018
1	lipoxin A4IBA 01/2018
1	PeriostinIBA 10/2016
1	MucinsIBA 02/2015
1	Sulfhydryl Compounds (Thiols)IBA 02/2015
1	CarbohydratesIBA 02/2015
1	GelsIBA 02/2015

Therapy/Procedure

1	Therapeutics 01/2019
1	Precision Medicine 10/2016